The term “alternative test method” means a test method that—
(A)includes any new or revised test method; and
(B)
(i)reduces the number of animals required;
(ii)refines procedures to lessen or eliminate pain or distress to animals, or enhances animal well-being; or
(iii)replaces animals with non-animal systems or one animal species with a phylogenetically lower animal species, such as replacing a mammal with an invertebrate.
(2) ICCVAM test recommendation
The term “ICCVAM test recommendation” means a summary report prepared by the ICCVAM characterizing the results of a scientific expert peer review of a test method.